Strategic Development and Manufacture of Novel Therapeutics
SeránCascade is a Contract Development & Manufacturing Organization (CDMO) founded by industry veterans with over 50 years of combined experience. SeránCascade provides rapid small molecule drug development and manufacturing services for our clients, both Active Pharmaceutical Ingredients (API) and Clinical Trial Materials (CTM), from Discovery to the Clinic. Our science-driven approach utilizes predictive design tools, novel chemistry, analytical tools, enabling delivery technologies, and extensive knowledge of quality and regulatory requirements for therapeutic compounds.
- Discovery Chemistry
- Process R&D
- Impurity Standards
- Animal Tox Batches
- GLP Tox Batches
- Parenteral & Ophthalmic
- Spray Drying
- Solid Dosage Form
Our synthetic team are experts in developing and executing complex syntheses, often scouting new routes for clients before IND or before moving into pivotal trials and validation. A long history of complex syntheses of natural products such as opiates, steroids & prostaglandins has given us experts in C-C bond formation, chiral control, development of difficult crystallizations, and protecting group scheme design. Additionally, we have significant experience with electron rich systems such as dyes, organic LEDs, and conductive organic polymers.
Our formulation team are experts in solubilization of poorly soluble compounds for both solid and liquid dosage forms. With over 20 years of spray drying experience and development of various drug product forms, we utilize a science-driven approach with predictive design tools, novel chemistry, analytical tools, enabling delivery technologies, and extensive knowledge of quality and regulatory requirements.
With a regulatory expert on staff, an expert designed electronic quality system, and a modern purpose built GMP facility, our integrated manufacturing helps clients rapidly get both API & CTM for Phase 1/2 studies.